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Insulin Pump Therapy: Evidence Based Medicine
Insulin Pump Therapy: Evidence Based Medicine
Saeid Kalbasi, MD
Associate Prof. of Endocrinology and Metabolism
Shahid Beheshti University of Medical Sciences
Research Institute of Endocrine Sciences
What is an insulin Pump?
- It is a pager sized, battery operated device.
- It provides a continuous insulin delivery over the 24 hours via a thin plastic tube ( infusion set) with a soft cannula at the end inserted subcutaneously.
- Insulin delivery is programmed with an individualized and unique plan suitable for each patient.
Pharmacokinetic Advantages
- Uses only Short Acting Insulin
- More predictable absorption than with modified insulins (variation 3-7% vs 20-50%*)
- Uses one injection site for 2 to 3 days
- Reduces variations in absorption due to site rotation
- Eliminates most of the subcutaneous insulin depot
- Programmable delivery allows closest match with physiologic needs
